Whenever submitting forms, make sure the footers are printed - barcode (if any), form number, form revision date, page number.
Never assemble form pages with different revision dates.
Make sure signatures are handwritten, not computer printer printed.
Prints or handwriting should be completely legible - no confusion as to whether it’s an e or c, it’s a 1 or lowercase L or uppercase i. The e/c problem is pretty common when people choose a small font size and the print is smudgy.