I've seen mixed responses from people on this, but nobody's 100% sure. I called the USCIS help-line too, and they said it wouldn't affect the I-765 as they're separate cases but they didn't seem too confident on the matter (lol)...
My appt was at 11:30am today, and the I-765 case status was changed to 'Case Is Being Actively Reviewed By USCIS' today!