Nobody knows for sure, but most likely your GF is going to be OK as long as she maintains status and files I-485 on time.
It's possible the in-person interviews are going to be required for most AOS applicants, like they were before COVID. Things may get more strict in terms of forms, following the process correctly. Already, you see USCIS saying they'll reject I-485 if no I-693 is provided, whereas in the past RFE was issued. So if you're sponsoring, make sure you have all valid documentation for taxes you filed and income you have. Find a joint sponsor sooner than later if you can't qualify on your own.
Things like that... I wouldn't think aliens in status will be affected much. But again, all of this is speculation.