You can submit. For marriage based case you're recommended to come to USCIS office for the interview. Most likely, you won't be needed, but occasionally officer needs to talk to US citizen spouse too.
For general provision, US citizen isn't required to attend at all.
Your spouse may need to answer deeper questions about marriage and you if filing under marriage rule.
Overall timeline for case may be longer based on 3 year rule, as it requires officers who know how to conduct it, more evidence needs to be reviewed and more checks into bonafide marriage may be needed.