US Immigration from Cameroon

Good day everyone. My Spouse just got approved for her Advance Parole and EAD at same time but when she came to the U.S with her K1 Visa, we leaved our kids back at her home country with her grand parents and Sisters. We still have the I-485 (Adjustment of Permanent Residence) pending waiting for approval. Our kids are not feeling to well and we plan on bringing them to join us as soon as things get better. But my question is, can my Spouse who came into the U.S with a K1 Fiance visa, now married and her Advance Parole Approved. Can she travel back to her home country (Cameroon) using her Country Valid Passport and Advance Parole while her I-485 is still pending and will she be question or face difficulties when re-entry the U.S. Thank you